Production of Lantipeptides in Escherichia coli

نویسندگان

  • Yanxiang Shi
  • Xiao Yang
  • Neha Garg
  • Wilfred A. van der Donk
چکیده

Lantipeptides are ribosomally synthesized and posttranslationally modified peptides containing thioether cross-links. We describe the preparation of seven different lantipeptides in Escherichia coli and demonstrate that this methodology can be used to incorporate nonproteinogenic amino acids.

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عنوان ژورنال:

دوره 133  شماره 

صفحات  -

تاریخ انتشار 2011